| Customization: | Available |
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| Classification: | Rapid Test Kit |
| Certification: | CE |
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DENGUE NS1 AG + IgG/IgM COMBO RAPID TEST CASSETTE
Description:
Dengue is a flavivirus, transmitted by Aedes aegypti and Aedes albopictus mosquitoes. It is widely distributed throughout the tropical and subtropical areas of the world,1 and causes up to 100 million infections annually.
2 Classic Dengue infection is characterized by a sudden onset of fever, intense headache, myalgia, arthralgia, and rash.
Primary Dengue infection causes IgM antibodies to increase to a detectable level in 3 to 5 days after the onset of fever. IgM antibodies generally persist for 30 to 90 days.3 Most Dengue patients in endemic regions have secondary infections,4 resulting in high levels of specific IgG antibodies prior to or simultaneous with IgM response.5 Therefore, the detection of specific anti-Dengue IgM and IgG antibodies can also help to distinguish between primary and secondary infections.
NS1 is one of 7 Dengue Virus non-structural proteins which are thought to be involved in viral replication.
NS1 exists as a monomer in its immature form but is rapidly processed in the endoplasmic reticulum to form a stable dimer. A small amount of NS1 remains associated with intracellular organelles where it is thought to be involved in viral replication. The rest of NS1 is found either associated with the plasma membrane or secreted as a soluble hexamer. NS1 is essential for viral viability but its precise biological function is unknown.
Antibodies raised in response to NS1 in viral infection can cross-react with cell surface antigens on epithelial cells and platelets and this has been implicated in the development of Dengue Hemorrhagic fever.
The Dengue IgG/IgM Rapid Test Cassette (Whole Blood/Serum/Plasma) is a rapid test that utilizes a combination of Dengue antigen-coated colored particles for the detection
of IgG and IgM Dengue antibodies in human whole blood, serum, or plasma.
The Dengue NS1 Rapid Test Cassette (Whole Blood/Serum/Plasma) is a rapid test that utilizes a combination of Dengue antibodies coated colored particles for the detection of Dengue NS1 antigen in human whole blood, serum, or plasma.
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